A high-dose IV iron used by patients across the globe for over 10 years

Monoferric is FDA approved to replace up to 1000 mg of iron in a single, rapid infusion*

Monoferric was introduced over 10 years ago as Monofer in the EU. Over 68 million dosesb have been administered outside of the US since launch, and it is available in more than 55 countries.

* Product labeling and characteristics may differ in other countries.
a Ferric derisomaltose is also known as iron isomaltoside 1000. Iron isomaltoside 1000 was the generic name initially approved in the European Union, whereas ferric derisomaltose is the international nonproprietary name and United States Adopted Name.
b As per the defined daily dose (DDD) definition by the World Health Organization (WHO). Outside the US, Monoferric is measured in 100-mg doses, as it is dosed per body weight. Within the US, Monoferric is measured in 1000-mg vials.
c 396,587 doses LTD through Nov 2025. Over 400k doses as of Dec 2025.
Monoferric is approved to replace 1000 mg of iron in one visit in appropriate patients

What to expect with Monoferric

Monoferric is used for treating iron deficiency anemia when you have previously tried oral iron medications and they have not worked. Monoferric is an intravenous iron treatment, meaning it is administered through your vein from a drip.

The nurse will stay with you during Monoferric treatment and for at least 30 minutes after to make sure you don’t have any type of reaction.

Benefits of Monoferric

Monoferric provides a slow release of iron into your system. The iron is used to create red blood cells, which will help to deliver oxygen throughout your body.

You also have access to the Monoferric Patient Solutions® Program that delivers diverse support to address your treatment needs. Check out the patient brochure to see everything the Monoferric Patient Solutions Program has to offer.

About the procedure

An infusion can take as little as 20 minutes. After the infusion, your doctor or a nurse will stay with you for 30 minutes to make sure you are feeling well before you leave.

Support

Your doctor can provide answers specific to your questions. If you have additional questions, Monoferric Patient Solutions Program is here for you before, during, or after treatment. Please give us a call if you have any questions. Just call the Monoferric Patient Solutions Program at 1-800-992-9022.

After treatment

In the weeks or months after treatment, a new blood sample will usually be taken to check your iron levels. By doing this, your doctor will be able to determine if you need more treatment.

Some patients need more than one treatment. If you have a long-lasting condition that is causing your iron deficiency anemia, it is normal to have your treatment repeated.

Download the Monoferric Patient Solutions Enrollment Form and complete with your doctor
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Monoferric Patient Solutions

IMPORTANT SAFETY INFORMATION

Monoferric is contraindicated in patients with a history of serious hypersensitivity to Monoferric or any of its components. Reactions have included shock, clinically significant hypotension, loss of consciousness, and/or collapse.

What is Monoferric?

Monoferric (ferric derisomaltose) is a prescription iron treatment given through a vein (IV) to treat iron deficiency anemia in adults who:

  • cannot tolerate oral iron or who have not responded well to treatment with oral iron
  • have non-dialysis dependent chronic kidney disease

IMPORTANT SAFETY INFORMATION

Who should not receive Monoferric?

Do not receive Monoferric if you have had serious allergic reactions to ferric derisomaltose or any of its ingredients.

What are the possible side effects of Monoferric?

Monoferric may cause serious side effects, including:

  • Allergic (hypersensitivity) reactions. Serious life-threatening allergic reactions have happened in people who receive Monoferric. Symptoms of an allergic reaction including rash, itching, hives, dizziness, lightheadedness, breathing problems, and low blood pressure have also happened during treatment with Monoferric. Tell your healthcare provider right away if you develop any of the above symptoms of a serious allergic reaction or if you have ever had any unusual or allergic reaction to any IV iron in the past.
  • Too much iron stored in your body (iron overload). Your healthcare provider should check the iron level in your blood before you start and during treatment with Monoferric.

The most common side effects of Monoferric include rash and nausea.

These are not all the possible side effects of Monoferric. Call your doctor for medical advice about side effects.

What should I tell my doctor or healthcare provider before receiving Monoferric?

Before receiving Monoferric, tell your healthcare provider about all your medical conditions, including if you:

  • have had an allergic reaction to IV iron.
  • are pregnant or plan to become pregnant. It is not known if Monoferric will harm your unborn baby. Untreated iron deficiency anemia during pregnancy may increase risks for you and your baby.
  • are breastfeeding or plan to breastfeed. Data from women treated with Monoferric show that iron is present in breast milk. It is not known how Monoferric may affect your breastfed baby.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

You are encouraged to report negative side effects to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see full Prescribing Information including information for patients.